Fioricet and Esgic are brand names of a combination of butalbital (a barbiturate), acetaminophen and caffeine which indicated for the treatment of tension headaches, muscle contraction headaches and post-dural puncture headaches. Although not indicated, they are commonly used to treat migraines and other pain related ailments.

Fioricet is indicated for the treatment of muscle tension or muscle contraction headaches. It is also commonly prescribed for migraines although it is not FDA indicated for this use in the United States. The usual adult dose is 1-2 tablets every four hours as needed, not exceeding six tablets in a 24-hour period.

Fioricet uses

Side effects of Fioricet

Fioricet side effects

Euphoria: is a mental and emotional state in which a person experiences intense feelings of well-being, elation,
happiness, excitement, and joy.Technically, euphoria is a psychological effect ,but the term is often colloquially used to define emotion and an intense state of transcendent happiness combined with an overwhelming sense of contentment. It has also been defined as an “effective state of exaggerated well-being or elationEuphoria.

Certain drugs, many of which are addictive, are known to produce a euphoric state. Certain natural rewards
such as physical exercise can also induce a state of euphoria.Euphoria has also been cited as being experienced by those participating in certain religious or spiritual rituals and meditation. Euphoria is also known to occur as a symptom of mania.

Dizziness :  Dizziness is an impairment in spatial perception and stability.Because the term dizziness is imprecise,
it can refer to vertigo, presyncope, disequilibrium, or a non-specific feeling such as giddiness or foolishness.One can induce dizziness by engaging in disorientating activities such as spinning.

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Vertigo is the sensation of spinning or having one’s surroundings spin about them. Many people find vertigo very disturbing and often report associated nausea and vomiting. It represents about 25% of cases of occurrences of dizziness.

dizziness

Vertigo is the sensation of spinning or having one’s surroundings spin about them. Many people find vertigo very disturbing and often report associated nausea and vomiting. It represents about 25% of cases of occurrences of dizziness.

Disequilibrium is the sensation of being off balance, and is most often characterized by frequent falls in a specific direction. This condition is not often associated with nausea or vomiting.

Presyncope is lightheadedness, muscular weakness and feeling faint as opposed to a syncope, which is actually fainting. Non-specific dizziness is often psychiatric in origin. It is a diagnosis of exclusion and can sometimes be brought about by hyperventilation.

Somnolence (alternatively “sleepiness” or “drowsiness”) is a state of strong desire for sleep, or sleeping for unusually long periods (compare hypersomnia). It has distinct meanings and causes. It can refer to the usual state preceding falling asleep, the condition of being in a drowsy state due to circadian rhythm disorders, or a symptom of other health problems. It can be accompanied by lethargy, weakness, and lack of mental agility.

Somnolence is often viewed as a symptom rather than a disorder by itself. However, the concept of somnolence recurring at certain times for certain reasons constitutes various disorders, such as excessive daytime sleepiness, shift work sleep disorder, and others; and there are medical codes for somnolence as viewed as a disorder.

Sleepiness can be dangerous when performing tasks that require constant concentration, such as driving a vehicle. When a person is sufficiently fatigued, microsleeps may be experienced.The word “somnolence” is derived from the Latin “somnus” meaning “sleep.”

Substance intoxication is a type of substance use disorder which is potentially maladaptive and impairing, but reversible, and associated with recent use.If the symptoms are severe, the term “substance intoxication delirium” may be used. Generic slang terms include: getting high or being stoned or blazed (all usually in reference to cannabis), with many more specific slang terms for each particular type of intoxicant. Alcohol intoxication is even graded in intensity, from buzzed, to tipsy, all the way up to hammered, smashed, wasted and a number of other similar terms Nausea  motion sickness”, “feeling sick or queasy” is a sensation of unease and discomfort in the upper stomach with an involuntary urge to vomit. It occasionally precedes vomiting. A person can suffer nausea without vomiting. When prolonged, it is a debilitating symptom.

Nausea is a non-specific symptom, which means that it has many possible causes. Some common causes of nausea are motion sickness, dizziness, migraine, fainting, gastroenteritis (stomach infection) or food poisoning. Nausea is a side effect of many medications including chemotherapy, nauseants or morning sickness in early pregnancy. Nausea may also be caused by anxiety, disgust and depression.

Medications taken to prevent and treat nausea are called antiemetics. The most commonly prescribed antiemetics in the US are promethazine, metoclopramide and ondansetron. Vomiting, also known as emesis and throwing up, among other terms, is the involuntary, forceful expulsion of the contents of one’s stomach through the mouth and sometimes the nose.

Vomiting can be caused by a wide variety of conditions; it may present as a specific response to ailments like gastritis or poisoning, or as a non-specific sequela of disorders ranging from brain tumors and elevated intracranial pressure to overexposure to ionizing radiation. The feeling that one is about to vomit is called nausea, which often precedes, but does not always lead to, vomiting. Antiemetics are sometimes necessary to suppress nausea and vomiting. In severe cases, where dehydration develops, intravenous fluid may be required. Vomiting is different from regurgitation, although the two terms are often used interchangeably. Regurgitation is the return of undigested food back up the esophagus to the mouth, without the force and displeasure associated with vomiting. The causes of vomiting and regurgitation are generally different.

Sedation is the reduction of irritability or agitation by administration of sedative drugs, generally to facilitate a medical procedure or diagnostic procedure. Drugs which can be used for sedation include propofol, etomidate, ketamine, fentanyl, and midazolam.

Substance dependence also known as drug dependence is an adaptive state that develops from repeated drug administration, and which results in withdrawal upon cessation of drug use. A drug addiction, a distinct concept from substance dependence, is defined as compulsive, out-of-control drug use, despite negative consequences.An addictive drug is a drug which is both rewarding and reinforcing. a gene transcription factor, is now known to be a critical component and common factor in the development of virtually all forms of behavioral addiction and drug addictions, but not dependence. Within the framework of the 4th edition of the Diagnostic and Statistical Manual of Mental Disorders  substance dependence is redefined as a drug addiction, and can be diagnosed without the occurrence of a withdrawal syndrome.It is now described accordingly.

When an individual persists in use of alcohol or other drugs despite problems related to use of the substance, substance dependence may be diagnosed. Compulsive and repetitive use may result in tolerance to the effect of the drug and withdrawal symptoms when use is reduced or stopped. This, along with Substance Abuse are considered Substance Use Disorders.

Dyspnea, dyspnoea, shortness of breath, or breathlessness is the feeling or feelings associated with impaired breathing. The American Thoracic Society defines it as “a subjective experience of breathing discomfort that consists of qualitatively distinct sensations that vary in intensity,” and recommends evaluating dyspnea by assessing the intensity of the distinct sensations, the degree of distress involved, and its burden or impact on activities of daily living. Distinct sensations include effort/work, chest tightness, and air hunger (the feeling of not enough oxygen).Dyspnea is a normal symptom of heavy exertion but becomes pathological if it occurs in unexpected situations. In 85% of cases it is due to asthma, pneumonia, cardiac ischemia, interstitial lung disease, congestive heart failure, chronic obstructive pulmonary disease, or psychogenic causes,such as panic disorder and anxiety. Treatment typically depends on the underlying cause.

Abdominal pain, also known as stomach pain or stomach ache, is a common symptom associated with both temporary, non-serious disorders and more serious conditions.

Common causes of pain in the abdomen include gastroenteritis and irritable bowel syndrome. In a third of cases the exact cause is unclear. About 10% of people have a more serious underlying condition such as appendicitis, leaking or ruptured abdominal aortic aneurysm, diverticulitis, or ectopic pregnancy. Determining the cause can be difficult, because many diseases can cause this symptom.

Overdose : The treatment of Fioricet overdose is complicated by the presence of two substances which are highly toxic when taken in excessive amounts. Fioricet overdoses generally result in toxic amounts of both acetaminophen and butalbital being consumed at once, requiring both overdoses to be treated at once. Fioricet overdose by anyone and/or any consumption by persons to whom it is not prescribed (particularly children) is always a medical emergency and medical attention must be sought immediately if an overdose or consumption by other persons is suspected.

Fioricet overdose is often fatal and symptoms may not present for hours following consumption; once initial overdose symptoms present they can progress rapidly and there may not be time to reach appropriate medical care after this point.Acetaminophen exerts its toxicity through the production of a toxic metabolite which can sometimes produce liver damage with doses as low as 4,000 mg, although normally requiring doses that are much higher. Acute liver failure may result in oses greatly exceeding this, and death has been known to occur with ingestion of 10,000-15,000 mg .

Acetaminophen he specific antidote to acetaminophen overdose is N-acetylcysteine. Acute renal failure and upper gastrointestinal bleeding may also occur. Butalbital exerts its toxicity through excessive sedation resulting in respiratory depression and ultimately death via hypoxia. Nonlethal overdoses may also result in coma and death. There is no specific antidote to barbiturate overdose and treatment is supportive. Common treatment regimens generally include the administration of intravenous administration of saline, naloxone, thiamine, glucose, sodium bicarbonate to alkalize the urine to increase rate of excretion, and activated charcoal via nasogastric tube. It is not uncommon for a doctor to recommend observation of the patient in the emergency department for a number of hours or admission to the hospital for several days of observation if symptoms are severe and to counsel the patient on drug abuse or refer them for psychiatric evaluation.

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